Guowei Wei received his Ph.D. degree from the University of British Columbia and is currently an MSU Research Foundation Professor at Michigan State University. He has pioneered novel computational methods that integrate profound mathematical structures with deep learning, leading to victories in D3R Grand Challenges, a worldwide competition series in computer-aided drug design, and the discovery of SARS-CoV-2 evolutionary mechanisms. He has earned numerous awards and honors, including the elected fellow of AIMBE. In addition, he has partnered with world premier pharmaceutical companies and the U.S. Food and Drug Administration (FDA) on drug discovery. Dr. Wei has served extensively on various national and international panels, committees, and journal editorships. Many of his former trainees now hold faculty positions in research universities worldwide.